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Understanding the limits and faulty assumptions in the ADOS will help us better understand ASD and will help us better characterize neurodevelopmental trajectories.
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Big Data Approaches to Decomposing Heterogeneity across the Autism Spectrum Using big data approaches will help us understand and model heterogeneity in the autism population, which is important for precision medicine and personalized support.
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Dysregulation in critical developmental networks identified in autism specific neurons derived from induced pluripotent stem cells (iPSCs).
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Widespread RNA editing dysregulation in brains from autistic individuals Abnormal RNA editing identified in post-mortem brains samples from individuals with autism.
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A complete protocol for analysis of data acquired from RNA and genome sequencing experiments.
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Abnormal dendritic spines from iPSCs derived pyramidal neurons from ASD patients.
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Cerebellar Modulation of the reward circuitry and social behavior The ventral tegmental area, a region involved in reward and social behavior, is linked directly to the cerebellum, a structure implicated in autism.
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Multiple genetic variants contribute to a more severe autism phenotype.
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Structure of brain matter in young autistic children may show distinct patterns
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